Πλοήγηση ανά Συγγραφέα "Patsouris, E."
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Activation of mTOR signaling in medullary and aggressive papillary thyroid carcinomas
Kouvaraki, M. A.; Liakou, C.; Paraschi, A.; Dimas, K.; Patsouris, E.; Tseleni-Balafouta, S.; Rassidakis, G. Z.; Moraitis, D. (2011)Background. Because mammalian target of rapamycin (mTOR) may be involved in thyroid carcinogenesis, we investigated the expression and activation patterns of mTOR signaling proteins in thyroid carcinoma cells and tumors ... -
Chromogenic in situ Hybridization Analysis of EGFR Gene Copies in Colon Adenocarcinoma Based on Intra-Operative Imprints and Tissue Microarrays
Tsiambas, E.; Rigopoulos, D. N.; Kravvaritis, C.; Lazaris, A. C.; Kavantzas, N.; Niotis, A.; Niotis, T. H.; Tsounis, D.; Karameris, A.; Patsouris, E. (2009)Background: Although Epidermal Growth Factor Receptor (EGFR) over expression is a frequent event in colon adenocarcinoma (CA), identification of EGFR gene deregulation mechanisms - combined to k-ras mutations - remains the ... -
Expression patterns of endothelin-1 and its receptors in colorectal cancer
Liakou, P.; Tepetes, K.; Germenis, A.; Leventaki, V.; Atsaves, V.; Patsouris, E.; Roidis, N.; Hatzitheophilou, K.; Rassidakis, G. Z. (2012)Background and Objectives Endothelin-1 (ET-1), a potent vasoconstricting peptide, plays an important role in carcinogenesis. Previous in vitro studies have shown that colorectal cancer cells produce ET-1. Methods: ET-1 and ... -
SIN1, a critical component of the mTOR-Rictor complex, is overexpressed and associated with AKT activation in medullary and aggressive papillary thyroid carcinomas
Moraitis, D.; Karanikou, M.; Liakou, C.; Dimas, K.; Tzimas, G.; Tseleni-Balafouta, S.; Patsouris, E.; Rassidakis, G. Z.; Kouvaraki, M. A. (2014)Background. Mammalian target of rapamycin (mTOR) forms 2 active complexes in the cell: the rapamycin-sensitive mTOR-Raptor (mTORC1) and the rapamycin-insensitive mTOR-Rictor (mTORC2). The latter activates AKT kinase, which ...